Cholesterol Synthesis and intake Fatty acids Low cholesterol link to cancer Hypercholesterolemia Children cholesterol test call In blood Marketing Function What is cholesterol? Regulation
The drug was billed as a super-statin during its clinical development; that it offered high potency and improved cholesterol reduction compared to rivals in the class. The main competitors to rosuvastatin are atorvastatin (Lipitor), and the combination product ezetimibe/simvastatin (Zetia+Zocor, together marketed as Vytorin by Merck & Co.). However, people can also combine ezetimibe with either rosuvastatin or atorvastatin and other agents on their own, for somewhat similar augmented response rates. So far, some published information for comparing rosuvastatin, atorvastatin and ezetimibe/simvastatin results is available, but many of the relevant studies are still in progress.
First launched in 2003, sales of rosuvastatin were $129 million and $908 million in 2003 and 2004, respectively, with a total patient treatment population of >4 million by the end of 2004.
In 2006, a new series of commercials were shown on TV, under the drug's trade name "Crestor". In the ads, Mandy Patinkin walks through a building with a series of hallways and escalators, a metaphor for the claim that Crestor was created to help raise good cholesterol and lower the bad — the promotional-phrase used was "down with the bad, up with the good". Patinkin, per FDA guidelines, also stated that the drug (like all statins) should not be used by pregnant persons, and to consult a doctor about using Crestor.